BCCP Board Certified Cardiology Pharmacist
BCCP Board Certified Cardiolog…
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1. A 64-year-old male with HFrEF (LVEF 32%) is currently receiving sacubitril/valsartan 97/103 mg twice daily, carvedilol 25 mg twice daily, and spironolactone 25 mg daily. His blood pressure is 112/74 mmHg, heart rate is 68 bpm, and his eGFR is 48 mL/min/1.73m². Despite adherence to this regimen for 6 months, he remains in NYHA Class II with persistent symptoms of fatigue. Which of the following is the most appropriate next step to optimize his guideline-directed medical therapy (GDMT)?
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